| Autor: |
Hati, Arpita, Mallick, Subhadeep, Baisya, Subhasmita, Banerjee, Shayeri, Chatterjee, Gobinda |
| Předmět: |
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| Zdroj: |
Journal of the Turkish Academy of Dermatology; 2022, Vol. 16 Issue 1, p24-26, 3p |
| Abstrakt: |
Porokeratosis is an acquired disorder of keratinization characterized by clonal expansion of keratinocytes which differentiate abnormally. All forms of porokeratosis have been reported to have familial clusters with autosomal dominant patterns of inheritance but with variable penetration. It is classified into the localized forms which include porokeratosis of Mibelli, linear porokeratosis (LP), and punctate palmoplantar porokeratosis, genital porokeratosis and perianal porokeratosis; the disseminated forms including disseminated superficial actinic porokeratosis, disseminated superficial porokeratosis (DSP), and disseminated palmoplantar porokeratosis and systematized LP. Disseminated superficial porokeratosis presents with multiple pink or red-brown finely scaly macules with a well defined raised border which appears in early adult life predominantly on extremities. The histopathology is characterized by thin column of tightly packed parakeratotic keratinocytes within a keratin filled invagination of the epidermis through stratum corneum known as cornoid lamella. It is associated with immunodeficiency or may appear spontaneously in childhood. Here we describe a young man with hyperkeratotic, hyperpigmented annular plaques distributed over extremities, trunk and face, mimicking disseminated discoid lupus erythematosus. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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