| Autor: |
Thanetchaiyakup, Adisak, Rattanarat, Hassayaporn, Aree, Sudaporn, Duangthongyou, Tanwawan, Nanok, Tanin, Chuanopparat, Nutthawat, Ngernmeesri, Paiboon |
| Předmět: |
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| Zdroj: |
Synthesis; 2022, Vol. 54 Issue 7, p1850-1856, 7p |
| Abstrakt: |
Melotenine A, isolated from Melodinus tenuicaudatus , possesses significant anticancer activity against several human cancer cell lines. The synthesis of (±)-melotenine A was achieved without the use of any protecting groups in 11 steps with an overall yield of 6.7%. The key steps of our strategy were a Diels–Alder reaction to construct the tetracyclic framework and ring-closing metathesis to form the seven-membered ring of (±)-melotenine A. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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