Improving Guideline-Congruent Care for Chemotherapy-Induced Nausea and Vomiting Prophylaxis in Pediatric Oncology Patients.

Autor: Diorio, Caroline, Vardaro, Julie, Yahui Wei, Mauro, Jane, Croy, Colleen, Oranges, Katelyn E., Flanagan, Lindsay, Reilly, Anne F., Charles Bailey, L., Jubelirer, Tracey, Elgarten, Caitlin W., Freedman, Jason L.
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Zdroj: JCO Oncology Practice; Mar2022, Vol. 18 Issue 3, pe412-e419, 8p
Abstrakt: PURPOSE Chemotherapy-induced nausea and vomiting (CINV) is a very common side effect of pediatric cancer therapy. High-quality, evidence-based, pediatric-specific guidelines for prophylaxis and treatment of CINV are available. At many centers, guideline-concordant care is uncommon. We formed a multidisciplinary quality improvement team to implement guideline-concordant care for CINV prophylaxis at our center. We present the results following the first year of our interventions. METHODS We planned and implemented a multipronged approach in three key phases: (1) developing and publishing an acute CINV prophylaxis pathway, (2) education of providers, and (3) updating the computerized provider order entry system. We used iterative, sequential Plan-Do-Study-Act cycles and behavioral economic strategies to improve adherence to guideline-concordant CINV prophylaxis. We focused on aprepitant usage as a key area for improvement. RESULTS At the beginning of the study period,, 50% of patients were receiving guideline-concordant CINV prophylaxis and, 15% of eligible patients were receiving aprepitant. After 1 year, more than 60% of patients were receiving guideline-concordant care and 50% of eligible patients were receiving aprepitant. CONCLUSION We describe the development and implementation of a standardized pathway for prevention of acute CINV in pediatric oncology patients. With a multidisciplinary, multifaceted approach, we demonstrate significant improvements to guideline-congruent CINV prophylaxis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index