Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) mRNA Vaccine-Breakthrough Infection Phenotype Includes Significant Symptoms, Live Virus Shedding, and Viral Genetic Diversity.

Autor:	Pollett, Simon D, Richard, Stephanie A, Fries, Anthony C, Simons, Mark P, Mende, Katrin, Lalani, Tahaniyat, Lee, Tida, Chi, Sharon, Mody, Rupal, Madar, Cristian, Ganesan, Anuradha, Larson, Derek T, Colombo, Christopher J, Colombo, Rhonda, Samuels, Emily C, Broder, Christopher C, Laing, Eric D, Smith, Darci R, Tribble, David, Agan, Brian K
Předmět:	BREAKTHROUGH infections VIRAL physiology SARS-CoV-2 ACQUISITION of data methodology COVID-19 vaccines RESEARCH methodology GENETIC variation INTERVIEWING SEVERITY of illness index MESSENGER RNA MEDICAL records QUESTIONNAIRES DESCRIPTIVE statistics POLYMERASE chain reaction PHENOTYPES
Zdroj:	Clinical Infectious Diseases; Mar2022, Vol. 74 Issue 5, p897-900, 4p
Abstrakt:	Little is known about severe acute respiratory syndrome coronavirus 2 "vaccine-breakthrough" infections (VBIs). Here we characterize 24 VBIs in predominantly young healthy persons. While none required hospitalization, a proportion endorsed severe symptoms and shed live virus as high as 4.13 × 103 plaque-forming units/mL. Infecting genotypes included both variant-of-concern (VOC) and non-VOC strains. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu