Chemical Review of Gorgostane-Type Steroids Isolated from Marine Organisms and Their 13 C-NMR Spectroscopic Data Characteristics.

Autor: Abdelkarem, Fahd M., Abouelela, Mohamed E., Kamel, Mohamed R., Nafady, Alaa M., Allam, Ahmed E., Abdel-Rahman, Iman A. M., Almatroudi, Ahmad, Alrumaihi, Faris, Allemailem, Khaled S., Assaf, Hamdy K.
Zdroj: Marine Drugs; Feb2022, Vol. 20 Issue 2, pN.PAG-N.PAG, 1p
Abstrakt: Gorgostane steroids are isolated from marine organisms and consist of 30 carbon atoms with a characteristic cyclopropane moiety. From the pioneering results to the end of 2021, isolation, biosynthesis, and structural elucidation using 13C-NMR will be used. Overall, 75 compounds are categorized into five major groups: gorgost-5-ene, 5,6-epoxygorgostane, 5,6-dihydroxygorgostane, 9,11-secogorgostane, and 23-demethylgorgostane, in addition to miscellaneous gorgostane. The structural diversity, selectivity for marine organisms, and biological effects of gorgostane steroids have generated considerable interest in the field of drug discovery research. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index