| Abstrakt: |
Objective: To assess the relationship between hs-CRP (high sensitivity C-reactive protein) and acute ST-elevation myocardial infarction (STEMI), and the association of hs-CRP with common coronary disease risk factors and angiographically important coronary artery disease. Study Design: A cross-sectional analytical study. Place and Duration: From 3rd Mar 2020 to 3rd Aug 2020 at the Department of Cardiology in Ch. Pervaiz Elahi Institute of Cardiology Multan. Methodology: A total of 150 patients diagnosed with STEMI were included in the study after passing through selection criteria. All the participants were evaluated for hypertension, diabetes, and smoking status. Blood samples were collected to analyze hs-CRP values following a protocol. Based on angiographic findings patients were divided into three groups: mild, moderated, and severe coronary artery disease. Results: The result found out significant relation between mean hs-CRP values and hypertension, diabetes, dyslipidemia, and Killip class (p<0.05). Although, the values of mean hs-CRP for double and triple coronary vascular diseases were higher than the single vascular disease (SVD, 0.62 mg/dl; DVD, 0.71 mg/dl and TVD, 0.87 mg/ml), no significant difference can be found in terms of a number of vessels involved. It was found out that mean hs-CRP values for three groups based on Syntax score are directly related to syntax scores. (Syntax score ≤22, 0.62 mg/ml; Syntax scores >22-32, 0.79 mg/ml and syntax score >32, 1.91 mg/dl), however, the difference remained insignificant. Conclusion: The study has found hs-CRP as a potential candidate for navigating the development of ST-elevation myocardial infarction and predicting its prognosis. [ABSTRACT FROM AUTHOR] |
