| Autor: |
Limami, Youness, Senhaji, Nezha, Zaid, Nabil, Khalki, Loubna, Naya, Abdallah, Hajjaj-Hassouni, Najia, Jalali, Farid, Oudghiri, Mounia, Zaid, Younes |
| Předmět: |
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| Zdroj: |
Seminars in Thrombosis & Hemostasis; Mar2022, Vol. 48 Issue 2, p246-250, 5p |
| Abstrakt: |
To further explore the signaling mechanism involved in the regulatory role of PKC in thrombin-induced platelet aggregation in CD patients, we assessed the phosphorylation of PKC on Tyr SP 311 sp and Thr SP 505 sp . In human platelets, pre-treatment with the specific PKC inhibitor significantly decreased platelet activation in patients with CD. The pathogenesis of inflammatory bowel diseases (IBD), representing chronic and relapsing-remitting disorders of the gastrointestinal tract, encompasses Crohn's disease (CD) and ulcerative colitis. [Extracted from the article] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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