| Autor: |
Rickmann, Annekatrin, Boden, Karl, Wahl, Silke, Trouvain, Andre, Schulz, Andre, Szurman, Peter |
| Zdroj: |
International Ophthalmology; Feb2022, Vol. 42 Issue 2, p401-409, 9p |
| Abstrakt: |
Purpose: To investigate the clinical outcome and complication rate of precut Descemet membrane endothelial keratoplasty (DMEK) in two different culture conditions, dextran-containing and dextran-free medium, and compare the results with the current standard DMEK procedure. Methods: A prospective study of 32 eyes suffering from Fuchs endothelial dystrophy were scheduled for DMEK with a follow-up of one year. The eyes were divided into four subgroups. Group + D (n = 7) received a precut DMEK stored in dextran-containing transport medium, and Group − D (n = 9) received a precut DMEK without dextran-containing medium. The respective fellow eyes received a standard DMEK (S) (preparation directly prior to surgery) stored in dextran-containing medium (S-D + ; n = 7) or without (S-D−; n = 9). Results: Clinical outcome (visual acuity, endothelial cell count, central corneal thickness) and rebubbling rate were comparable for all four groups. None of the patients had a graft failure. Conclusion: The preliminary data of the pilot study show that precut liquid-bubble DMEK leads to comparable clinical results regardless of dextran-containing or dextran-free organ culture medium and is further comparable to the standard DMEK procedure. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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