| Abstrakt: |
Objectives: The current study aimed to investigate the role of of anti-Müllerian hormone (AMH) and other hormonal biomarkers and insulin resistance in pathogenesis of polycystic ovarian syndrome (PCOS) of Iraqi women with various ages and body mass index (BMI). Method: The sublects include 50 cases of PCOS obtained from gynecological and obstetric teaching hospital, Kerbala health directorate/ Kerbala -- Iraq and another 50 apparently healthy women as a control group. with age ranged between 18and 37 years during the period from Dec. 2019 to June, 2020 which was divided into two groups depending upon their age; first group with age (18-27) years and the second with age (28-37) years. Also, they were divided into three subgroups depending upon the BMI, normal weight (18.5--24.9 kg/m2), overweight (25--29.9 kg/m2), obesity (30--34.9 kg/m2) and measurement of various hormonal levels were performed including luteinizing hormone (LH), follicle stimulating hormone (FSH), insulin, insulin resistance, total testosterone, and AMH. Results: A significant elevated levels of each of AMH, insulin, LH, total testosterone, prolactin, fasting blood glucose and insulin resistance while, a non-significant differences was found in FSH levels in women with PCOS as compared with control group. Conclusion: A significant high level of the all hormonal parameters including AMH, LH, prolactin and total testosterone was found in women with PCOS as compared with the control, except the FSH values. [ABSTRACT FROM AUTHOR] |
