Pathological role of neuroendocrine cells in infants with persistent tachypnoea - are they only bystanders?

Autor: Miraftabi, Päria, Kirjavainen, Turkka, Föhr, Anna, Lohi, Jouko, Martelius, Laura
Předmět:
Zdroj: Acta Paediatrica; Mar2022, Vol. 111 Issue 3, p636-637, 2p
Abstrakt: The 38 infants with a clinical presentation of NEHI were divided into 11 with NEHI, with an NEC count of 10% or more, 11 with NEHI-like disease, with an NEC count of less than 10% and 16 with NEHI syndrome, where no lung biopsy had been taken (Figure 1). All infants with NEHI and NEHI-like disease had normal lung histology and we ruled out ongoing interstitial lung disease with normal follow-up, high-resolution lung CTs and an extensive 114 gene pulmonology panel. Abbreviations CT computerised tomography NEC neuroendocrine cell NEHI neuroendocrine cell hyperplasia of infancy Neuroendocrine cell hyperplasia of infancy (NEHI) is the most common interstitial childhood lung disease. [Extracted from the article]
Databáze: Complementary Index