Cobalt-Catalyzed Hydroxyperfluoroalkylation of Alkenes with Perfluoroalkyl Bromides and Atmospheric Oxygen.

Autor: Sun, Qilin, Pang, Liangzhi, Mao, Shuxian, Fan, Wu, Zhou, Yuyi, Xu, Jing, Li, Suhua, Li, Qiankun
Předmět:
Zdroj: Synthesis; Mar2022, Vol. 54 Issue 5, p1353-1364, 12p
Abstrakt: A mild and efficient method for the cobalt-catalyzed hydroxyperfluoroalkylation of alkenes has been developed. This method demonstrated broad substrate scope, good yields, and mild conditions with the tolerance of mono-, di-, and trisubstituted alkenes including both styrenes and non-activated aliphatic olefins. This strategy offered a valuable solution for rapid and efficient construction of β-perfluoro-alkyl alcohols using widely available and inexpensive perfluoroalkyl bromides- and atmospheric oxygen. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index