| Abstrakt: |
Background: Chronic wound is when there is no complete healing after 6 weeks or poor response to a treatment change. Although any wound has the potential to become chronic, medical conditions commonly associated with chronic/non-healing wounds are diabetes mellitus, chronic venous congestion, arterial insufficiency and pressure sores. We are compared efficacy of collagenase (enzymatic debridement) and hydrogel dressing (autolytic debridement in management of chronic wounds at a tertiary health centre. Material and Methods: This prospective, comparative study, with in-patients more than 18 years admitted in Shri B.M Patil Medical College and Hospital, Vijayapura, Karnataka, India. Patients were randomised by lottery method, Group A-20 patients treated with collagenase dressings & Group B-20 patients treated with hydrogel dressings. Results: Total 40 patients were taken for the study. Age & gender distribution (Table 1) statistically not significant. Most patients were from 41-70 years age group, male to female ratio was approximately 2:1 in both groups. It was noted that complete responder, partial responder, non-complete responder & non-responder patients in group A were 65%, 20%, 10% & 5%. While in group B complete responder, partial responder, non-complete responder & non-responder patients were 50%, 15%, 25% & 10%. Difference between complete responder (completely healed) & non-complete responder (less than 50% reduction from the baseline area) was statistically significant in group A & group B Conclusion: Both hydrogel & collagenase are good options in management of chronic wounds. Experience was better with collagenase, larger studies are required for future guidelines. [ABSTRACT FROM AUTHOR] |
