| Autor: |
De Martino, Mara, Daviaud, Camille, Vanpouille-Box, Claire |
| Předmět: |
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| Zdroj: |
OncoImmunology; 2021, Vol. 10 Issue 1, p1-3, 3p |
| Abstrakt: |
The mechanisms accountable for the infiltration of regulatory T cells into an irradiated tumor remain elusive. In our recent study, we demonstrate that activin A promotes regulatory T cells in tumors, and impairs anti-tumor immune responses induced by radiotherapy and TGF-β blockade. Dual blockade of activin A and TGF-β may be necessary to reduce regulatory T cells mediated immunosuppression driven by radiation therapy. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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