Bullous SDRIFE and Covid‐19.

Autor: Bonamigo, Renan Rangel, Bottega, Gustavo Borchardt, Staub, Fernanda Luiza, Almeida, Rodrigo Oliveira, Werka, Hellen Meyre Grosskopf
Předmět:
Zdroj: International Journal of Dermatology; Mar2022, Vol. 61 Issue 3, p372-374, 3p
Abstrakt: Could this reaction, particularly if accompanied by vasculitis and thrombosis, be a marker of severe outcomes of SARS-CoV-2 infection? Dear Editor, Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE) is a drug reaction with well-defined criteria and some clinical and histopathological variability, in addition to simultaneous overlapping features with other pharmacological reactions.1,2 We report a special case of SDRIFE with bullae formation in a patient with severe COVID-19, a situation that is unmatched in the literature. Histopathology showed marked epidermal spongiosis, mild interface dermatitis, and dermal edema, inflammatory infiltrate with eosinophils and leukocytoclastic vasculitis with focal thrombi (Fig. [Extracted from the article]
Databáze: Complementary Index