3‐Pyrazolyl‐oxindoles as efficient nucleophiles for construction of 3,3′‐diheterocycle substituted oxindoles using chitosan as reusable catalyst in water.

Autor:	Liu, Li, Wang, Qing‐He, Li, Yue, Wu, Ming‐Shu
Předmět:	OXINDOLES CATALYSTS NUCLEOPHILES CHITOSAN COLUMN chromatography MALONONITRILE
Zdroj:	Journal of Heterocyclic Chemistry; Feb2022, Vol. 59 Issue 2, p388-393, 6p
Abstrakt:	A facile, one‐pot, environmentally benign and chitosan‐catalyzed protocol for the construction of a novel 3,3′‐diheterocycle substituted oxindole framework by three‐component reaction between 3‐pyrazolyl‐oxindoles, salicylaldehydes, and malononitrile in water is reported. This protocol provides several advantages including readily available starting materials, a simple operation, without the need of purification by column chromatography, reusable catalyst. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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