| Autor: |
Mertha Adnyana, I. Made Dwi, Sudaryati, Ni Luh Gede, Sitepu, Israil |
| Předmět: |
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| Zdroj: |
Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia; Oct-Dec2021, Vol. 32 Issue 4, p514-521, 8p |
| Abstrakt: |
Community-based DHF vector control has been implemented in Indonesia but has not yet obtained optimal results. Thus, in the community choosing synthetic insecticides to control disease vectors. Long term and excessive using of insecticides enable a toxic effect and resistance to mosquitoes. Burning of mosquitoes coils and incense containing synthetic dyes and fragrances have the potential to reduce environmental quality. This research was conducted to analyze the toxicity of Legiayu incense as an insecticide and larvicide against Aedes aegypti mosquito mortality. The research design is experimental with a completely randomized design. Testing was conducted by providing exposure to smoke and ash of Legiayu incense five times on twenty-five Aedes aegypti mosquitoes. Statistical analysis used one-way ANOVA, and probit test. The result showed that insecticides effective exposure for 20 minutes with a durability of 6 hours (p=0.000), while as larvicide effective exposure for 24 hours (p=0.000). Exposure Legiayu incense smoke obtained an LT50 value of 09012 ≤ 5 (super toxic category) with a time of 15 minutes 39 seconds, R2 of 99.24%, and r of 99.62% while exposure to the ash of Legiayu incense obtained LT50 value of 0,05896 ≤ 5 (super toxic category) with time 19 hours 15 minutes 34 seconds, R2 and r of 100%. Histopathological test results showed that Legiayu incense smoke did not cause tissue degeneration, necrosis, hyperplasia, and metaplasia in the lung tissue of mice (Mus musculus) in 12 weeks period. Thus, Legiayu incense is effective as insecticides and larvicides against Aedes aegypti mosquitoes and potential substitute for mosquito repellent synthetic incense. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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