Estimated Prevalence and Number of Persons With Isolated Antibody to Hepatitis B Core Antigen and Associated Occult Hepatitis B, United States, 2001-2018.

Autor:	Spradling, Philip R, Xing, Jian, Harris, Aaron M, Ly, Kathleen N
Předmět:	HEPATITIS associated antigen HEPATITIS B HEALTH & Nutrition Examination Survey IMMUNOGLOBULINS VIRAL antigens RESEARCH LIVER tumors DNA RESEARCH methodology HEPATITIS viruses EVALUATION research SURVEYS COMPARATIVE studies DISEASE prevalence VIRAL antibodies
Zdroj:	Journal of Infectious Diseases; Feb2022, Vol. 225 Issue 3, p465-469, 5p
Abstrakt:	Persons with isolated antibody to hepatits B virus (HBV) core antigen (IAHBc) may have occult HBV infection (OBI), which is associated with reactivation and potential risk for hepatocellular carcinoma and HBV transmission. We used National Health and Nutrition Examination Survey data to estimate US IAHBc prevalence and published studies of IAHBc-associated OBI prevalence to estimate OBI burden. During 2001-2018, the prevalence of IAHBc was 0.8% (approximately 2.1 million persons), and the OBI burden range was 35 500-83 600 persons. These data support the need for more robust estimates of IAHBc-associated OBI prevalence in the general US population. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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