| Autor: |
Gotsko, Maxim D., Saliy, Ivan V., Sobenina, Lyubov N., Ushakov, Igor A., Kireeva, Victoriya V., Trofimov, Boris A. |
| Předmět: |
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| Zdroj: |
Synthesis; Feb2022, Vol. 54 Issue 4, p1134-1144, 11p |
| Abstrakt: |
An efficient method for the synthesis of 1 H ,1′ H -2,3′-bi-pyrroles (up to 72% yield) by the cyclocondensation of easily available 2-(acylethynyl)pyrroles with diethyl aminomalonate hydrochloride has been developed. The reaction proceeds under reflux in MeCN (6 h) in the presence of Cs2 CO3. Under the same conditions, 2-(acylethynyl)pyrroles with bulky (benzyl and octyl) substituents at nitrogen atom react with diethyl aminomalonate to afford 1 H ,2′ H -2,3′-bipyrroles and pyrrolyl-aminopyrones. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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