Iron therapy as a novel treatment of scleroderma‐related pulmonary hypertension: A case report and literature review.

Autor:	Neumann, Melissa, Wong, Karen A., Lazo, Kevin, Stover, Diane
Předmět:	PULMONARY hypertension PULMONARY arterial hypertension SYSTOLIC blood pressure LITERATURE reviews SYSTEMIC scleroderma IRON
Zdroj:	Respirology Case Reports; Feb2022, Vol. 10 Issue 2, p1-4, 4p
Abstrakt:	Pulmonary arterial hypertension (PAH) is the leading cause of death in patients with systemic sclerosis (SSc), with a 3‐year mortality of 40%–50% despite optimal therapy. Treatment mirrors that of idiopathic PAH and is often ineffective. This is a case report of a patient with SSc evaluated for progressive dyspnoea with exertion and found to have elevated pulmonary artery systolic pressures (PASPs). She received ferritin‐targeted iron infusions as a novel treatment of suspected SSc‐associated PAH, with subsequent resolution of respiratory symptoms and PASPs that normalized. We review PAH especially associated with SSc, its treatment and identify a possible novel therapeutic approach for those with PAH‐SSc. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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