| Autor: |
Jagiełło-Gruszfeld, Agnieszka, Niwińska, Anna, Michalski, Wojciech, Pogoda, Katarzyna, Dubiański, Roman, Kunkiel, Michał, Lemańska, Izabela, Sienkiewicz, Renata, Górniak, Anna, Kosakowska, Ewa, Nowecki, Zbigniew |
| Předmět: |
|
| Zdroj: |
Oncology in Clinical Practice (2450-1654); 2021, Vol. 17 Issue 6, p237-243, 7p |
| Abstrakt: |
A retrospective observational study of the outcomes of darbepoetin alfa treatment for chemotherapy-induced anaemia in breast cancer patients was conducted. A group of 152 patients treated during 13 months in one oncology centre was assessed. Ninety-eight patients (64.5%) received perioperative chemotherapy, and 54 patients (35.5%) received palliative chemotherapy. The results of treatment with darbepoetin alfa were analysed by age (< 65 vs. ≥ 65 years), the aim of chemotherapy (perioperative vs. palliative), and body mass index (< 25 vs. 25-29 vs. 30 and more). The effectiveness of the therapy was estimated at 80.9% (95% CI: 74.7-87.2%). Significantly higher effectiveness of ESA was found in patients treated perioperatively compared to patients treated for metastatic breast cancer (85.7% vs. 72.2%, p = 0.043). There were no differences in the effectiveness of ESA depending on age and BMI. No serious ESA-related adverse events were observed. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
