Structural variation of the 3-acetamido-4,5,6-trihydroxyazepane iminosugar through epimerization and C-alkylation leads to low micromolar HexAB and NagZ inhibitors.

Autor: Bouquet, J., Auberger, N., Ashmus, R., King, D., Bordes, A., Fontelle, N., Nakagawa, S., Madden, Z., Proceviat, C., Kato, A., Désiré, J., Vocadlo, D. J., Blériot, Y.
Zdroj: Organic & Biomolecular Chemistry; 1/21/2022, Vol. 20 Issue 3, p619-629, 11p
Databáze: Complementary Index