| Autor: |
Fındık, Mükerrem, Uçar, Asuman, Akgemci, Emine Güler |
| Předmět: |
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| Zdroj: |
Celal Bayar University Journal of Science; 2021, Vol. 17 Issue 4, p387-395, 9p |
| Abstrakt: |
Cu(II) complex of 2-hydroxy-5-methoxyacetophenone-N(4)-ethyl thiosemicarbazone (Cu(HMAET)Cl) was synthesized and characterized by spectroscopic methods such as FT-IR, ¹H-NMR and UV-Vis. The Cu(II) complex's DNA-binding capacity was studied with the UV-Vis absorption titration and ethidium bromide (EB) displacement experiment using E. coli DNA. The results demonstrated that the Cu(II) complex could intercalate in the DNA's base pairs. The binding constant was found as 2.8x107 M-1. Also, the interaction study of the Cu(II) complex with bovine serum albumin (BSA) was investigated using the UV-Vis absorption and fluorescence spectroscopy techniques. It was concluded that the Cu(II) complex interacts strongly with BSA. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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