| Autor: |
Plotnikova, Kateryna, Dubenska, Liliya, Rydchuk, Petro, Pysarevska, Solomiya, Rydchuk, Mariana, Ivakh, Sophia, Yanovych, Dmytro, Zasadna, Zvenyslava, Plotycya, Serhiy |
| Předmět: |
|
| Zdroj: |
Journal of Food Measurement & Characterization; Feb2022, Vol. 16 Issue 1, p891-900, 10p |
| Abstrakt: |
The method of voltammetric determination of nitroimidazoles in honey is developed. This method is based on the reduction of nitroimidazoles nitro group on the mercury drop indicator electrode. The obtained values of LODs for nitroimidazoles are as follows: 1.5 × 10−7 M, 8.6 × 10−8 M and 2.0 × 10−7 M for metronidazole, dimetridazole, and ipronidazole, and the linear correlation coefficients are 0.99974, 0.99987 and 0.99849, respectively, which tend towards to 1. The minimum amount of metronidazole that can be detected by means of our method, using simple dissolving of honey sample in water is 300 µg of metronidazole per 1 kg of honey. The developed voltammetric technique's accuracy was confirmed by the "added-found" method and by HPLC-MS/MS analysis. The calculated amount of metronidazole in the tested model solution is in good agreement with the amount, introduced into honey. The calculated values of texp are 0.52, 0.48 and 0.43 for three different concentrations. Significant advantages of the method are effortless sample preparation, fast procedure of analysis, the possibility of miniaturization, low cost, not necessary use of organic solvents. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink