A Self‐locked β‐Cyclodextrin‐rhodamine B Spirolactam with Photoswitching Properties.

Autor: Panagiotakis, Stylianos, Saridakis, Emmanuel, Malanga, Milo, Mavridis, Irene M., Yannakopoulou, Konstantina
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Zdroj: Chemistry - An Asian Journal; 1/17/2022, Vol. 17 Issue 2, p1-10, 10p
Abstrakt: Supramolecular organization and self‐assembly are the pillars of functionality of many nanosystems. The covalent conjugate (6‐spirolactam rhodamine B‐6‐monodeoxy)‐β‐cyclodextrin (Rho‐βCD) is assembled as a self‐included, rigid nanostructure, identical in the crystal and in aqueous solution, as revealed by detailed X‐ray and NMR analyses. Rho‐βCD self‐assembly is the result of an interesting reaction pathway, which partially de‐aggregates Rho and disturbs the zwitterion↔spirolactone equilibrium. Rho‐βCD is stable at pH 4.6, but displays controllable photoswitching between the colored, fluorescent, zwitterionic and the colorless, non‐fluorescent closed structures, during several iterative cycles. After an initial drop in absorbance, the on‐off process continues without further changes under our irradiation conditions, a consequence of the specific self‐locked arrangement of Rho in the cavity. Rho‐βCD exemplifies a water soluble photoresponsive nanosystem with improved photostability suggesting promising applications in super resolution bioimaging. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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