ROLE OF IL-23 AND IL-10 IN PATHOGENESIZ OF PREGNANT WOMEN WITH UT INFECTION IN DIYALA GOVERNORATE.

Autor: Khudhair, Samer Yaseen, Nazzal, Maha Falih
Předmět:
Zdroj: Biochemical & Cellular Archives; Oct2021, Vol. 21 Issue 2, p3571-3573, 3p
Abstrakt: Urinary tract infections (UTIs) are the most common type of bacterial infection during pregnancy and untreated can be associated with serious obstetric complications. Women are usually more likely to get UTIs with more serious complications. Antimicrobial agents are the first line of treatment for UTIs. The aim of the study was to detect the levels of IL10 and IL23. The study included (45) samples of pregnant women patients with urinary tract infection after diagnosis by obstetricians and gynecologists and it was divided into three periods, the first period included the first three months (1, 2, (3) and the second period It included the months (4,5,6) of pregnancy and the last period included the last three months (7, 8, 9) of pregnancy, where (15) samples were taken from each of the three stages of pregnancy for infected pregnant women and (45) samples were collected From apparently healthy pregnant women as a control group from the three pregnancies. The serum was separated and the above cytokine levels were detected and the enzyme-linked immunosorbent reaction (ELISA) method was used. The results also showed an increase in the IL-23 level in the patients (707.9061±9061 pg/ ml) compared to the control group (198.1445 ± 171.3316 pg/ml) at a significant level p-value £ 0.05 and the level of IL-10 in patients was reduced (50.1296 ± 4.8345 pg/ml) compared to the control group (55.6142 ± 12.7402 pg/ml) at a significant level p-value £ 0.05. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index