Trimethylsilyl Esters as Novel Dual-Purpose Protecting Reagents.

Autor: Chen, Jyun-Siao, Huang, Po-Hsun, Hsieh, Ya-Chi, Liu, Jen-Wei, Hsu, Hsiao-Lin, Zhang, Kai-Min, Wu, Ren-Tsung, Chang, Ting-Shuo, Liu, Yu-Hao, Wu, Hsin-Ru, Luo, Shun-Yuan
Předmět:
Zdroj: Synthesis; Feb2022, Vol. 54 Issue 3, p754-762, 9p
Abstrakt: Trimethylsilyl esters, AcOTMS, BzOTMS, TCAOTMS, etc., are inexpensive and chemically stable reagents that pose a negligible environmental hazard. Such compounds prove to serve as efficient dual-purpose reagents to respectively achieve acylation and trimethylsilylation of alcohols under acidic or basic conditions. Herein, a detailed study on protection of various substrates and new methodological investigations is described. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index