| Autor: |
Sabir, Samina Aliya, Qazi, Qudsia, Abbas, Ghulam, Zeb, Laila, Yasmin, Sumaira |
| Předmět: |
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| Zdroj: |
Journal of Medical Sciences (1997-3438); Oct2021, Vol. 29 Issue 4, p269-272, 4p |
| Abstrakt: |
Objective: To compare the effectiveness of Basal bolus and Premixed Insulin regimen in gestational and type 2 diabetic pregnant patients. Material and methods: This randomized controlled trial was conducted in Obstetrics and Gynecology department, Lady Reading Hospital (LRH) Peshawar over a period of one year from January to December 2020. A total of 100 patients with Type 2 Diabetes and Gestational Diabetes were included in the study. These 100 patients were divided into two groups. Group 1 was allocated to patients given Basal Bolus Regimen and Group 2 was allocated to patients given Pre-mixed twice daily Insulin. Patients were allocated to each group randomly by lottery method. The patients were put on insulin according to body weight after the first 24-hour blood sugar profile. Results: The two groups were comparable for maternal age (34.6±4.68, 34.6±5.11, p-value = 0 .775), gestational age (34.2±1.65, 34.0±1.34, and p value = .552), gravidity (7.08±1.65, 6.68±1.5, p-value of 0.434). HBA1C in the two groups were similar (7.40±.742 and 7.39±.751 with a p-value of 0.947), with mean blood glucose (calculated by average of 2 readings of postprandial levels) in the two groups in first 24 hours were comparable (MBG 24Hrs Group 1= 341.54±46, Group 2 =344.08±47 p-value = 0.784). There was a rapid control of blood sugar, on day 7 with Basal Bolus regimen with Mean Blood Glucose (MBG) 152±9.798mg/dL as compared to Premixed split regimen which was 192.4±14.99 mg/dL Conclusion: The Basal bolus regimen is more effective than the premixed insulin regimen in controlling blood sugar in pregnant patients with diabetes. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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