Effects of glucagon‐like peptide‐1 receptor agonists on histopathological and secondary biomarkers of non‐alcoholic steatohepatitis: A systematic review and meta‐analysis.

Autor: Borodavkin, Petr, Sheridan, William, Coelho, Claudia, Oštarijaš, Eduard, Zaïr, Zoulikha M., Miras, Alexander D., McGowan, Barbara, le Roux, Carel W., Vincent, Royce P., Dimitriadis, Georgios K.
Předmět:
Zdroj: Diabetes, Obesity & Metabolism; Feb2022, Vol. 24 Issue 2, p337-342, 6p
Abstrakt: C) Effects of GLP-1RA's on GGT concentration in patients with NASH compared to placebo. BACKGROUND Non-alcoholic steatohepatitis (NASH) is manifested by ectopic fat accumulation on the liver tissue without a secondary cause. FIGURE S1: PRISMA 2009 flow diagram (8).FIGURE S2: A) Effects of GLP-1RA's on AST concentration in patients with NASH compared to placebo. In addition, we compared for the first time the secondary markers of NASH other than aminotransferase levels, which may be utilized to supplement the results of GLP-1RA treatment on histological aspects of NASH. [Extracted from the article]
Databáze: Complementary Index