Detection of extra-cardiac hypermetabolic foci by [18F]FDG PET/CT in case of infective endocarditis and post antibiotic therapy response assessment.

Autor: Jain, Anurag, Hegde, Arun, Kumar, A. V. S. Anil, Sharma, Amit, Husain, Azhar
Předmět:
Zdroj: Iranian Journal of Nuclear Medicine; Winter/Spring2022, Vol. 30 Issue 1, p67-71, 5p
Abstrakt: The diagnosis of prosthetic valve endocarditis continues to present a diagnostic challenge, due to the lower sensitivity of the modified Duke criteria and a higher percentage of negative or inconclusive echocardiography results. Diagnostic delay might result in significant morbidity/mortality. Imaging modalities like 2-[18F]fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography ([18F]FDG PET/CT), prove to be an added diagnostic modality in such cases, thus assisting the accuracy of diagnosis by the modified-Duke-criteria. [18F]FDG PET/CT can prove highly beneficial, provided proper preparation for adequate suppression of the physiological myocardial uptake is done prior to the scan, thus helping is semiquantitative analysis of the infected focus. We herein, report a case of suspected infective endocarditis with known prior history of a prosthetic valve in situ where the diagnosis of infective endocarditis could not be established with conviction, despite the use of conventional modalities of imaging like 2D echocardiography. [18F]FDG PET/CT proved its mettle by determining the primary site of infection, as well as metastatic extra-cardiac infective foci, and thus avoiding morbidity arising out of delayed diagnosis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index