| Autor: |
MOHANAN, SREELAKSHMI, NAIR, GEETHA, MALIEKKAL, JEAN |
| Předmět: |
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| Zdroj: |
Journal of Clinical & Diagnostic Research; Dec2021, Vol. 15 Issue 12, p6-9, 4p |
| Abstrakt: |
Introduction: Type 2 Diabetes Mellitus (T2DM) has emerged as a major public health concern globally and it is associated with a multitude of complications leading to mortality and morbidity. A close association has been observed with T2DM and obesity in various studies, which has been closely associated with intraabdominal or central obesity rather than to overall adiposity. Aim: To evaluate the association of T2DM with anthropometric parameters, abdominal obesity parameters and Insulin Resistance (IR). Material and Methods: A case-control study was conducted amongst diabetic patients attending the diabetic clinic of a tertiary care centre over a period of one year. Participants aged between 30 to 75 years were recruited. The abdominal obesity anthropometric parameters which included Body Mass Index (BMI), Waist Circumference (WC), Waist Hip Ratio (WHR), Waist Height Ratio (WHtR) were recorded. IR was estimated using Homeostasis Model Assessment (HOMA)-IR method. The matching controls were recruited. Data was entered in Microsoft Excel software and data was analysed using Statistical Package for the Social Sciences (SPSS) software version 16.0. Results: A 64 T2DM patients and 64 normal healthy controls were included in the study. The mean BMI was 23.1±2.3 and 21.3±1.2 for cases and controls, respectively (p-value <0.001). The mean WC was 84.0±4.8 and 80.5±2.8 (p-value=0.003), and mean WHR was 0.9±0.3 and 0.8±0.02 (p-value <0.001) for cases and controls respectively. The mean WHtR was 0.5±0.1 and 0.5±0.03 (p-value=0.330), and mean IR was 3.8±1.1 and 1.3±0.2 (p-value <0.001) for cases and controls respectively. A statistically significant positive correlation was observed between IR and WC of T2DM patients (p-value=0.025). A statistically insignificant positive correlation was observed between IR and BMI (p=0.105). Conclusion: BMI, abdominal obesity parameters and IR values were elevated in T2DM. Among the anthropometric parameters studied, WHtR was observed to be a better parameter and it can be used routinely in a clinical setting. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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