Pre-analytical recommendations and reference values for circulating calprotectin are sample type and assay dependent.

Autor: Nevejan, Louis, Mylemans, Marnix, Vander Cruyssen, Bert, Stubbe, Muriel, Van Den Bremt, Stefanie, Hofman, Laura, Infantino, Maria, Manfredi, Mariangela, Bossuyt, Xavier, Van Hoovels, Lieve
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Zdroj: Clinical Chemistry & Laboratory Medicine; Jan2022, Vol. 60 Issue 2, pe57-e60, 4p
Abstrakt: Keywords: biomarker; circulating calprotectin; neutrophil-related inflammation; pre-analytical phase; reference values EN biomarker circulating calprotectin neutrophil-related inflammation pre-analytical phase reference values e57 e60 4 01/07/22 20220115 NES 220115 To the Editor, Fecal calprotectin (CLP) is universally applied for diagnosis and follow-up of inflammatory bowel diseases (IBD) [[1]], reflecting local disease activity in the gut [[3]]. Table 1: Circulating calprotectin measured in serum with gel separator, lithium heparin, EDTA and citrate plasma (Sarstedt S-MONOVETTE SP ® sp ) (µg/mL [[8]]) in 100 healthy volunteers. Critical role of pre-analytical aspects for the measurement of circulating calprotectin in serum or plasma as a biomarker for neutrophil-related inflammation. [Extracted from the article]
Databáze: Complementary Index