| Autor: |
Salciccia, Stefano, Rosati, Davide, Viscuso, Pietro, Canale, Vittorio, Scarrone, Emiliano, Frisenda, Marco, Catuzzi, Roberta, Moriconi, Martina, Asero, Vincenzo, Signore, Stefano, De Dominicis, Mauro, Emiliozzi, Paolo, Carbone, Antonio, Pastore, Antonio Luigi, Fuschi, Andrea, Di Pierro, Giovanni Battista, Gentilucci, Alessandro, Cattarino, Susanna, Mariotti, Gianna, Busetto, Gian Maria |
| Předmět: |
|
| Zdroj: |
Central European Journal of Urology (2080-4806); 2021, Vol. 74 Issue 4, p503-515, 13p |
| Abstrakt: |
Introduction The aim of this article was to analyze whether operative time and blood loss during radical prostatectomy (RP) can significantly influence surgical margins (SM) status and post-operative functional outcomes. Material and methods We prospectively analyzed prostate cancer (PC) patients undergoing RP, using robot-assisted (RARP) or laparoscopic (LRP) procedures. Blood loss was defined using the variation in hemoglobin (Hb, g/dl) values from the day before surgery and no later than 4 hours after surgery. Results From a whole population of 413 cases considered for RP, 67% underwent LRP and 33.0% RARP. Positive SM (SM+) were found in 33.9% of cases. Mean surgical operative time was 172.3 ±76 min (range 49-485), whereas blood loss was 2.3 ±1.2 g/dl (range 0.3-7.6). Operative time and blood loss at RP were not significantly correlated (r = -0.028275; p = 0.684). SM+ rates significantly (p = 0.002) varied by operative time; a higher SM+ rate was found in cases with an operative time <120 min (41.2%) and >240 min (53.4%). The risk of SM+ significantly increased 1.70 and 1.94 times in cases with an operative time <120 min and >240 min, respectively, independently to the surgical approach. The rate of erectile disfunction (ED) varied from 22.4% to 60.3% between <120 min and >240 min procedures (p = 0.001). According to blood loss, SM+ rates slightly but significantly (p = 0.032) varied; a higher rate of SM+ was found in cases with a Hb variation between 2-4 g/dl (35.9%). Conclusions Independently to the surgical approach, operative time, more than blood loss at RP, represents a significant variable able to influence SM status and post-operative ED. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
