Fish collagen as a potential indicator of severe allergic reactions among patients with fish allergies.

Autor: Shimojo, Naoshi, Yagami, Akiko, Ohno, Fumiaki, Tsurumi, Yuta, Nakamura, Masashi, Suzuki, Kayoko, Kuwabara, Kazunobu, Futamura, Kyoko, Ohno, Satoshi, Yokogawa, Takashi, Horiguchi, Takahiko, Matsunaga, Kayoko
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Zdroj: Clinical & Experimental Allergy; Jan2022, Vol. 52 Issue 1, p183-187, 5p, 3 Charts
Abstrakt: In this study, we focused on the relationship between severity and IgE reactivity against fish collagen, and our results suggest that it may be possible to detect patients with severe fish allergy by measuring collagen-specific IgE. Recently, the clinical relevance of fish collagen was investigated in a large patient population ( I n i = 101).9 The inclusion of relevant collagen allergens in routine diagnosis has shown to improve the ability to accurately diagnose fish allergy. Keywords: allergen component; anaphylaxis; component-resolved diagnostics; ELISA; fish collagen EN allergen component anaphylaxis component-resolved diagnostics ELISA fish collagen 183 187 5 01/05/22 20220101 NES 220101 Key Message We investigated the relationship between symptom severity and IgE reactivity to specific allergens in fish. Sensitivity to fish collagen is under-reported because of solubility problems and false-negative SPT results.10 SPT, using heated fish extract, is very useful for diagnosing fish collagen-induced allergy. [Extracted from the article]
Databáze: Complementary Index
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