| Autor: |
Le, Kieu Hung, Bui, Thi Kim Ngan, Pham, Nguyen Kim Tuyen, Dang, Van Son, Ngo, Trong Nghia, Phan, Nhat Minh, Bui, Trong Dat, Tran, Trong Duc, Nguyen, Quan Hien, Ngo, Quoc Luan, Mai, Dinh Tri, Nguyen, Tan Phat |
| Předmět: |
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| Zdroj: |
Natural Product Research; Jan 2022, Vol. 36 Issue 1, p165-170, 6p |
| Abstrakt: |
From the Vietnamese plant Macrosolen tricolor (Lecomte) Danser, one new diarylpropanoid, named macrotricolorin A (1) together with three diarylheptanoids including bisdemethoxycurcumin (2), demethoxycurcumin (3) and curcumin (4), were isolated. Their structures were elucidated by intensive analyses of their IR, UV, HR-ESI-MS and NMR (1 D & 2 D) spectra. It is the first time that diarylalkanoids have been reported from the genus Macrosolen. Compound 1 exhibited anti-inflammatory activity against the nitric oxide (NO) production in lipopolysaccharide (LPS)-induced RAW264.7 with an IC50 value of 27.54 ± 1.75 μM. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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