Triglycerides/high-density lipoprotein-cholesterol ratio in children with metabolic syndrome.

Autor: Ruiz-Jaramillo, Ma. De La Cruz, López-Acevedo, Mauricio
Předmět:
Zdroj: Child & Adolescent Obesity (2574254X); Dec 2021, Vol. 4 Issue 1, p78-88, 11p
Abstrakt: The incidence of metabolic syndrome in children is increasing due to the obesity epidemic. Accessible biochemical studies are required to diagnose and treat it in a timely manner. This cross-sectional study aims to assess the usefulness of the triglycerides/high-density lipoprotein-cholesterol (TG/HDL-c) index as a predictor of metabolic syndrome according to the diagnostic criteria of the European initiative Identification and prevention of Dietary- and lifestyle-induced health EFects In Children and infantS (IDEFICS) in obese children 3 to 10 years of age. Descriptive, observational, retrospective study in the pediatric service of León General Hospital, Guanajuato, México, from January 2017 to December 2018. In a group of 73 obese children aged 3 to 10 years, it was found that the TG/HDL-c ratio has an odds ratio of 6 (95% CI 2–18) as a predictor of metabolic syndrome. A cut-off point of 2.4 for this index has a sensitivity of 85%, specificity of 85%, likelihood ratio of 5.6, positive predictive value of 94%, and negative predictive value of 68% to diagnose metabolic syndrome with IDEFICS criteria. The TG/HDL-c index is a useful indicator to diagnose metabolic syndrome in children 3 to 10 years of age with obesity, in whom it is not possible to perform a comprehensive biochemical study. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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