| Autor: |
Kaliszczak, Magdalena, Durand, Pierrick, Wenger, Emmanuel, Dossot, Manuel, Jones, Franca, Arrigan, Damien W. M., Herzog, Grégoire |
| Předmět: |
|
| Zdroj: |
CrystEngComm; 1/7/2022, Vol. 24 Issue 1, p48-51, 4p |
| Abstrakt: |
Controlled formation of cocrystals is an important objective in drug development. Here, cocrystallisation of caffeine and 1-hydroxy-2-naphthoic acid was investigated at the interface between two immiscible electrolyte solutions under chemical polarisation. In this way, selective cocrystallisation was achieved, as verified by X-ray diffraction and Raman spectroscopy. Positive interfacial potentials favoured the formation of one polymorphic form of caffeine:1-hydroxy-2-naphthoic acid cocrystal. This approach to electrochemically controlled cocrystallisation opens up new possibilities for drug development. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
