Should Allele Testing Be Done Before Prescribing Allopurinol to Prevent Severe Cutaneous Adverse Reactions?

Autor: Close, Elizabeth, Keyes, Andrew, Burden, Jonathan, Bray, Corey, Migdalski, Alyssa
Předmět:
Zdroj: American Family Physician; Nov2021, Vol. 104 Issue 5, p513-514, 2p
Abstrakt: The article discusses prescribing allopurinol to prevent severe cutaneous adverse reactions (SCARs) such as Stevens-Johnson syndrome. It mentions effectiveness of allele testing in populations reportedly at increased risk; and also mentions problems associated with comparing HLA frequencies across racial, ethnic, or geographic groups.
Databáze: Complementary Index