Natural Products as Potential Antiviral Drugs: The Specific Case of Marine Biotoxins.

Autor: Jean-Louis Kraus
Předmět:
Zdroj: Russian Journal of Bioorganic Chemistry; Nov2021, Vol. 47 Issue 6, p1127-1132, 6p
Abstrakt: To fight against various viral infections researchers turned to new chemical structures resulting from natural medicinal plants and more recently from "marine origin" as sources of active molecules against viral infections. The present manuscript describes complex marine origin drugs, their chemical complex structure, their therapeutic use, and their antiviral properties. Emphasis is placed more particularly on the properties of ionic channels (Na+, K+, Ca2+) blockers compounds from marine origin, named Dinotoxins, derived from "dinoflagellates microalgae". These compounds are of particular pharmaceutical interest since ionic channels blockers could be used to fight against a wide diversity of viruses, including SARS-CoV2 virus. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index