| Autor: |
HUEY NEE NG, MING HAN LING, SIU MIN LIM, ZAINAL ABIDIN MF |
| Předmět: |
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| Zdroj: |
Medicine & Health (Universiti Kebangsaan Malaysia); 2021 Supplement, Vol. 16, p71-71, 1p |
| Abstrakt: |
Objectives: To assess the efficacy and compliance of a timely antibiotic administration antibiotic (within 60 minutes prior to surgical skin incision) educational campaign in reducing postoperative surgical skin infections (SSI). Methods: This is an observational before (phase 1) and after (phase 2) study performed at University Malaya Medical Centre. Patients recruited were orthopedic cases involving implant insertions/removals from the semi-emergency trauma list. Patients with pre-existing infection and/or receiving regular antibiotics were excluded from the study. Control group (n=113) patients received antibiotic prophylaxis based on existing protocols with timing of administration subjected to knowledge and experience of the individual anesthetist. Treatment group patients (n=132) received antibiotic after an personal educational reminder to emphasize on timely administration of antibiotic prophylaxis. Timing of antibiotic delivery and incidence of SSI based on clinical findings were documented. Results: There was no significant difference in incidence of SSI in patients who received prophylactic antibiotic within 60 minutes versus more than 60 minutes before skin incision (3.2% vs 7.3%, P = 0.174). Subgroup analysis revealed patient groups who received antibiotic prophylaxis within 30-60 minutes prior to skin incision had zero incidence of SSI which is statistically significant compared to those received antibiotic prophylaxis within 30 minutes or more than 60 minutes prior to skin incision (0% vs 6.7% vs 7.3%, P=0.0073) (boferroni correction significant if P<0.0083). There was a substantial improvement in compliance of timely prophylactic antibiotic administration in the Phase 2 post educational group within 60 mins (13.9 % vs 26.9%, p =.000). Conclusion: Administration of antibiotics prophylaxis within 30-60 mins prior to skin incision is associated with significantly lower incidence of SSI. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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