Pigmented epidermotropic breast cancer metastases: A rare variant with a particularly unusual feature.

Autor: Torre‐Castro, Juan, Moya‐Martínez, Cristina, Haya‐Martínez, Lara, Mendoza‐Cembranos, María Dolores, Eraña‐Tomás, Itziar, Requena, Luis
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Zdroj: Journal of Cutaneous Pathology; Jan2022, Vol. 49 Issue 1, p99-102, 4p, 3 Color Photographs, 1 Graph
Abstrakt: Pigmented epidermotropic breast cancer metastases are a rarity, often clinically misdiagnosed as melanocytic lesions. Histopathologically, they show a dermal proliferation of neoplastic metastatic cells that extend to the overlying epidermis in a pattern identical to that seen in primary Paget disease (PD). Differential diagnosis should be established with entities with a similar presentation, such as pigmented mammary PD and malignant melanoma. Immunohistochemistry may be useful for this purpose. We present a new case of pigmented epidermotropic breast cancer metastases with a particularly unusual feature: the absence of dermal infiltration by neoplastic cells, thus considered as pure epidermotropic metastatic involvement. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index
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