Kidney biopsies in control or cyclosporin A- treated psoriatic patients.

Autor: Mihatsch, M.J., Belghiti, D., Bohman, S.O., Porter, K., Dubertret, L., Fry, L., Juhlin, L., Zachariae, H., Feutren, G.
Předmět:
Zdroj: British Journal of Dermatology; Jun1990 Supplement 36, Vol. 122, p95-100, 6p
Abstrakt: Kidney biopsies were obtained from 14 adult patients treated with cyclosporin A (CyA) for psoriasis. These biopsies were compared with those from 16 psoriatic patients of the same age, but who were not receiving treatment with CyA. Patients receiving CyA had a maximum mean dose of 5·1 mg/kg/day for a mean duration of 15 months (range 3–37 months). Minimal or slight interstitial fibrosis, tubular atrophy or arteriolopathy were seen in the biopsies of patients receiving CyA as well as in those of the controls. No relevant CyA-related structural alterations of the kidney were detected. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index