| Autor: |
Zelin Zhao, Siteng Wu, Weina Ren, Qinxiang Zheng, Cong Ye, Kim, Andy D., Jhanji, Vishal, Wang, Michael T. M., Wei Chen |
| Zdroj: |
British Journal of Ophthalmology; Dec2021, Vol. 105 Issue 12, p1645-1650, 6p |
| Abstrakt: |
Aims To compare the efficacy of compression sutures combined with intracameral air injection (CSAI) and thermokeratoplasty (TKP) for the management of acute corneal hydrops in keratoconus. Methods In this multi-centre randomised clinical trial, 20 patients with keratoconus (20 eyes) with acute corneal hydrops were enrolled and randomised to receive either CSAI or TKP and followed-up for a period of 6 months. Results There were no significant differences in patient demographics, severity of corneal hydrops and preoperative duration of symptoms between the two groups. In both groups, corneal oedema resolved within 2 weeks. The maximum thickness of the corneal scars following CSAI and TKP was not significantly different. Best spectacle-corrected visual acuity was superior in the CSAI group at 6-month follow-up (CSAI vs TKP, 0.52 (0.37, 0.85) vs 0.96 (0.70, 1.34) LogMAR, p=0.042). CSAI resulted in greater corneal endothelial cell density (CSAI vs TKP, 2677.8±326.7 vs 1955.3±298.1 cells/mm2, p<0.001) and flatter corneal curvature (CSAI vs TKP: mean keratometry value, 52.13±4.92 vs 63.51 ±5.83D, p<0.001; maximum keratometry value, 65.21 ±7.42 vs 77.13±12.01D, p=0.016) at the 6-month follow-up. Conclusion Although both CSAI and TKP resulted in resolution of acute corneal hydrops in keratoconus, CSAI was associated with superior clinical outcomes in this study. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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