| Autor: |
Guo, Luxia, Li, Jiaqi, Vaccaro, Luigi, Li, Minghao, Gu, Yanlong |
| Předmět: |
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| Zdroj: |
Green Chemistry; 12/7/2021, Vol. 23 Issue 23, p9465-9469, 5p |
| Abstrakt: |
N-Aryl/alkyl 3-carbonylpyrroles are ubiquitous in compounds of biological and material significance, whereas their synthesis traditionally requires a multistep protocol. Herein a kalinite catalyzed direct synthesis of N-substituted 3-carbonylpyrroles from a 2,2-dimethoxyacetaldehyde derived Morita–Baylis–Hillman acetate and a primary amine in ethanol is developed. This reaction is scalable and also applicable to the synthesis of JMH-030, JMC-2004 and other bioactive compounds. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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