| Abstrakt: |
This special issue offers a broad overview of current knowledge of the molecular and genetic mechanisms that underly neurodegenerative processes; present in various diseases of the central nervous system (CNS) such as Alzheimer's (AD), Parkinson's (PD), and temporal lobe epilepsy (TLE) among others. In the same way, it reduced the apoptosis pathways, and MaR1 significantly improved cognitive impairment and enhanced cell survival, suggesting that inflammation resolution may be a potential therapeutic target for AD (Yin et al.). In PD, damaged dopaminergic neurons are capable of causing neuroinflammation, oxidative stress, and cytokine-receptor-mediated apoptosis; this favors peripheral leukocyte recruitment, generating a feedback mechanism that results in exacerbation of the neurodegenerative process. Keywords: neurodegeneration; oxidative stress; reactive oxygen species; dementia; inflammation EN neurodegeneration oxidative stress reactive oxygen species dementia inflammation 1 4 4 11/22/21 20211117 NES 211117 Among non-transmissible chronic diseases, neurodegenerative complications have become a big challenge in public health. [Extracted from the article] |
