| Autor: |
Zehetner, Verena, Lipnik, Karoline, Url, Angelika, Heus, Phebe de, Fröhlich, Wolfgang, Cavalleri, Jessika-M. V., Berger, Sonja |
| Předmět: |
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| Zdroj: |
Pferdeheilkunde; Sep/Oct2021, Vol. 37 Issue 5, p488-496, 9p |
| Abstrakt: |
A 26-year old donkey gelding was referred to the University Equine Hospital of the Vetmeduni Vienna for evaluation of increased respiratory rate and dyspnoea of 2 weeks duration as well as chronic weight loss. Radiography and ultrasonography of the thorax revealed an interstitial lung pattern, pulmonary oedema and a large number of comet tail artefacts. Echocardiography detected severe aortic valve regurgitation and a dilated pulmonary artery indicating pulmonary hypertension. A diagnosis of interstitial fibrosis was made on histopathology of a lung biopsy. The donkey moderately improved with dexamethasone and furosemide treatment. It subsequently developed ventricular tachycardia followed by multifocal ventricular premature beats. Antiarrhythmic therapy was unsuccessful and the donkey was euthanised when in an agonal state. Necropsy and histopathology confirmed severe lung fibrosis similar to previously reported cases affected by Donkey Pulmonary Fibrosis (DPF) as well as dilatation and degeneration of the pulmonary arterial wall consistent with pulmonary hypertension. PCR analysis of bronchoalveolar fluid sampled post-mortem revealed asinine herpesvirus (AHV) 5 DNA. This report aims at highlighting the clinical signs, diagnostic workup and histopathologic features of DPF. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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