The Efficacy of Pentazocine + Diclofenac versus Paracetamol + Diclofenac for Post-Caesarean Section Analgesia.

Autor: Garba, Jamila Abubakar, Panti, Abubakar Abubakar, Nnadi, Daniel C., Ango, Ibrahim G., Tunau, Karima A., Bello, Saratu, Zubairu, Saad, Nasir, Asmau'u Muhammad, Ibrahim, Rukayya
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Zdroj: Nigerian Postgraduate Medical Journal; Jul-Sep2021, Vol. 28 Issue 3, p187-192, 6p
Abstrakt: Background: The most common major obstetric procedure is caesarean section (CS) and one of the greatest concerns for women after CS is to have optimal pain relief. Aim: This study aims to compare the efficacy of pentazocine + diclofenac and paracetamol + diclofenac on post-operative analgesia after CS. Methodology: This was a single-blind, randomised trial. Pregnant women that had CS were randomized into two groups. Group A received intramuscular pentazocine + rectal diclofenac postoperatively. Group B received intramuscular paracetamol + rectal diclofenac postoperatively. Post-operative pain was assessed by numeric rating scale at 1 h after the surgery, at 6 h, 12 h and 24 h. The result obtained was analysed using SPSS Version 22 and P < 0.05 was considered statistically significant. Results: The median pain scores in both groups ranged from 2 to 3 across all periods of assessment. The pain relief was slightly better in the pentazocine + diclofenac group with no significant difference in the pain score between the two groups at all periods of assessment. The satisfaction level was good in 66.3% and 69.5% of the participants in the pentazocine + diclofenac and paracetamol + diclofenac group respectively but the difference was not statistically significant (X² = 4.14, P = 0. 12). Nausea, vomiting and drowsiness were significantly more in the pentazocine + diclofenac combination (P < 0.001). Conclusion: Both combination of analgesics provided adequate analgesia but pentazocine + diclofenac combination had better pain relief but was more associated with side effects. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index