| Abstrakt: |
Background: Regional anesthesia is frequently used in obstetric, orthopedic, and urological procedures, commonly intrathecal and epidural local anesthetics are combined with opioids to prolong analgesia; however, these do not prolong the motor block time and can attenuate the response to surgical stress, in addition to being associated with side effects such as respiratory depression, urinary retention, pruritus, hemodynamic instability, nausea, and emesis. Objective: to investigate the effect of adding 75 mg of magnesium sulfate on the duration of sensory block and duration of motor block Patients and Methods: In a prospective randomized study, ASA I or II, 128 (64 control and 64 experimental groups) pregnant women (at term) who were candidate for cesarean section with spinal anesthesia, were recruited in this study. They were collected from "Baghdad Teaching Hospital" at the period from (September 2020 to Fab 2021). Each experimental woman received 12.5 mg (2.5 ml) of hyperbaric bupivacaine (0.5%) and 0.5 ml (75 mg) magnesium sulfate (15%), while controls received same does of hyperbaric bupivacaine and 0.5 ml of distilled water. Results: The duration of analgesia (sensory blockade) and theduration of motor blockade manifested a statistically significant increase inexperimental as compared to their controls (control = 116.41 ± 12.47, experimental = 159.75 ± 10.56, control = 180.76 ± 11.83, experimental = 240 ±9.46 minutes respectively). Conclusion:Significantly increased the duration of postoperative analgesia and prolonged the sensory and motor blockade withoutsignificant apparent maternal or fetal side effects. [ABSTRACT FROM AUTHOR] |
