| Autor: |
Astakhov, Grigorii S., Shigaev, Rinat R., Borisova, Tatiana N., Ershova, Anastasia A., Titov, Alexander A., Varlamov, Alexey V., Voskressensky, Leonid G., Matveeva, Maria D. |
| Zdroj: |
Molecular Diversity; Nov2021, Vol. 25 Issue 4, p2441-2446, 6p |
| Abstrakt: |
A convenient protocol for the synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines with various electron-withdrawing substituents at C-2 atom is described. This approach is based on the two-component domino reaction of 1-aroyl-3,4-dihydroisoquinolines with α,β-unsaturated ketones, nitroalkenes and acrylonitrile. Depending on the selected substrates, the reaction was performed in TFE under reflux or under microwave irradiation. Only for the two examples, a transition metal catalyst was used. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
|
Full text from SpringerLink