| Autor: |
Bodian, Semyon, Colchester, Richard J., Macdonald, Thomas J., Ambroz, Filip, Briceno de Gutierrez, Martha, Mathews, Sunish J., Fong, Yu Man Mandy, Maneas, Efthymios, Welsby, Kathryn A., Gordon, Ross J., Collier, Paul, Zhang, Edward Z., Beard, Paul C., Parkin, Ivan P., Desjardins, Adrien E., Noimark, Sacha |
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| Zdroj: |
Advanced Materials Interfaces; 10/22/2021, Vol. 8 Issue 20, p1-9, 9p |
| Abstrakt: |
Dual‐modality imaging employing complementary modalities, such as all‐optical ultrasound and photoacoustic imaging, is emerging as a well‐suited technique for guiding minimally invasive surgical procedures. Quantum dots are a promising material for use in these dual‐modality imaging devices as they can provide wavelength‐selective optical absorption. The first quantum dot nanocomposite engineered for co‐registered laser‐generated ultrasound and photoacoustic imaging is presented. The nanocomposites developed, comprising CuInS2 quantum dots and medical‐grade polydimethylsiloxane (CIS‐PDMS), are applied onto the distal ends of miniature optical fibers. The films exhibit wavelength‐selective optical properties, with high optical absorption (> 90%) at 532 nm for ultrasound generation, and low optical absorption (< 5%) at near‐infrared wavelengths greater than 700 nm. Under pulsed laser irradiation, the CIS‐PDMS films generate ultrasound with pressures exceeding 3.5 MPa, with a corresponding bandwidth of 18 MHz. An ultrasound transducer is fabricated by pairing the coated optical fiber with a Fabry–Pérot (FP) fiber optic sensor. The wavelength‐selective nature of the film is exploited to enable co‐registered all‐optical ultrasound and photoacoustic imaging of an ink‐filled tube phantom. This work demonstrates the potential for quantum dots as wavelength‐selective absorbers for all‐optical ultrasound generation. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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