Structure and expression of two members of the d4 gene family in mouse.

Autor: Mertsalov, Ilja B., Kulikova, Dina A., Alimova-Kost, Maria V., Ninkina, Natalia N., Korochkin, Leonid I., Buchman, Vladimir L.
Předmět:
Zdroj: Mammalian Genome; Jan2000, Vol. 11 Issue 1, p72-74, 03p
Abstrakt: This article focuses on d4 gene family. The d4 family is a group of unique, evolutionarily conserved zinc finger proteins that are involved in the determination of cell fate. The first member of the d4 family, neuro-d4, was cloned as a neuro specific, developmentally regulated rat gene. The most characteristic feature of these proteins is a cysteine/histidine-rich C-terminal d4-domain, a double-paired finger motif that consists of two tandemly arranged PHD finger domains. More recently, two additional members of the neuro-d4 family have been identified in the human, mouse, and chicken genomes.
Databáze: Complementary Index
Externí odkaz: